| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CHEK1 | SETMAR | Ser508 | LYDNRRRsAQWLDQE | phosphorylation down-regulates activity | 25024738 | SIGNOR-273610 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CHEK1 | phosphorylation up-regulates → | SETMAR PSer508 | phosphorylation down-regulates ⊣ | SETMAR | 25024738 | SIGNOR-273610 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CHEK1 | phosphorylation → down-regulates activity | SETMAR | SIGNOR-273610 |
