Entity Details

Name SGO1
ID Q5FBB7
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AURKASGO1–phosphorylation
up-regulates activity		16824953SIGNOR-252046
CDK1SGO1Thr346LEEGVHLtPFRQKVSphosphorylation
up-regulates activity		24055156SIGNOR-265263
NEK2SGO1Ser507TDLCFLNsPIFKQKKphosphorylation
up-regulates		17621308SIGNOR-156882
NEK2SGO1Ser14LKKSFQDsLEDIKKRphosphorylation
up-regulates		17621308SIGNOR-156878
BUB1SGO1–phosphorylation
up-regulates quantity by stabilization		19015261SIGNOR-278915
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK1phosphorylation
up-regulates
→
SGO1
PThr346		phosphorylation
up-regulates
→		SGO124055156SIGNOR-265263
NEK2phosphorylation
up-regulates
→
SGO1
PSer507		phosphorylation
up-regulates
→		SGO117621308SIGNOR-156882
NEK2phosphorylation
up-regulates
→
SGO1
PSer14		phosphorylation
up-regulates
→		SGO117621308SIGNOR-156878
Regulator Mechanism/Effect Target SIGNOR-ID
AURKAphosphorylation
→
up-regulates activity 		SGO1SIGNOR-252046
CDK1phosphorylation
→
up-regulates activity 		SGO1SIGNOR-265263
NEK2phosphorylation
→
up-regulates 		SGO1SIGNOR-156882
NEK2phosphorylation
→
up-regulates 		SGO1SIGNOR-156878
BUB1phosphorylation
→
up-regulates quantity by stabilization 		SGO1SIGNOR-278915