| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCD | HABP4 | Thr354 | RKPANDItSQLEINF | phosphorylation down-regulates activity | 14699138 | SIGNOR-249248 |
| PRKCQ | HABP4 | Thr375 | GRGARGGtRGGRGRI | phosphorylation down-regulates activity | 14699138 | SIGNOR-249256 |
| PRKCZ | HABP4 | Thr354 | RKPANDItSQLEINF | phosphorylation down-regulates activity | 14699138 | SIGNOR-249251 |
| PRKCA | HABP4 | Thr375 | GRGARGGtRGGRGRI | phosphorylation down-regulates activity | 14699138 | SIGNOR-249252 |
| PRKCB | HABP4 | Thr375 | GRGARGGtRGGRGRI | phosphorylation down-regulates activity | 14699138 | SIGNOR-249253 |
| PRKCQ | HABP4 | Thr354 | RKPANDItSQLEINF | phosphorylation down-regulates activity | 14699138 | SIGNOR-249250 |
| PRKCG | HABP4 | Thr375 | GRGARGGtRGGRGRI | phosphorylation down-regulates activity | 14699138 | SIGNOR-249255 |
| PRKCA | HABP4 | Thr354 | RKPANDItSQLEINF | phosphorylation down-regulates activity | 14699138 | SIGNOR-249246 |
| PRKCB | HABP4 | Thr354 | RKPANDItSQLEINF | phosphorylation down-regulates activity | 14699138 | SIGNOR-249247 |
| PRKCZ | HABP4 | Thr375 | GRGARGGtRGGRGRI | phosphorylation down-regulates activity | 14699138 | SIGNOR-249257 |
| PRKCG | HABP4 | Thr354 | RKPANDItSQLEINF | phosphorylation down-regulates activity | 14699138 | SIGNOR-249249 |
| PRKCD | HABP4 | Thr375 | GRGARGGtRGGRGRI | phosphorylation down-regulates activity | 14699138 | SIGNOR-249254 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCD | phosphorylation up-regulates → | HABP4 PThr354 | phosphorylation down-regulates ⊣ | HABP4 | 14699138 | SIGNOR-249248 |
| PRKCQ | phosphorylation up-regulates → | HABP4 PThr375 | phosphorylation down-regulates ⊣ | HABP4 | 14699138 | SIGNOR-249256 |
| PRKCZ | phosphorylation up-regulates → | HABP4 PThr354 | phosphorylation down-regulates ⊣ | HABP4 | 14699138 | SIGNOR-249251 |
| PRKCA | phosphorylation up-regulates → | HABP4 PThr375 | phosphorylation down-regulates ⊣ | HABP4 | 14699138 | SIGNOR-249252 |
| PRKCB | phosphorylation up-regulates → | HABP4 PThr375 | phosphorylation down-regulates ⊣ | HABP4 | 14699138 | SIGNOR-249253 |
| PRKCQ | phosphorylation up-regulates → | HABP4 PThr354 | phosphorylation down-regulates ⊣ | HABP4 | 14699138 | SIGNOR-249250 |
| PRKCG | phosphorylation up-regulates → | HABP4 PThr375 | phosphorylation down-regulates ⊣ | HABP4 | 14699138 | SIGNOR-249255 |
| PRKCA | phosphorylation up-regulates → | HABP4 PThr354 | phosphorylation down-regulates ⊣ | HABP4 | 14699138 | SIGNOR-249246 |
| PRKCB | phosphorylation up-regulates → | HABP4 PThr354 | phosphorylation down-regulates ⊣ | HABP4 | 14699138 | SIGNOR-249247 |
| PRKCZ | phosphorylation up-regulates → | HABP4 PThr375 | phosphorylation down-regulates ⊣ | HABP4 | 14699138 | SIGNOR-249257 |
| PRKCG | phosphorylation up-regulates → | HABP4 PThr354 | phosphorylation down-regulates ⊣ | HABP4 | 14699138 | SIGNOR-249249 |
| PRKCD | phosphorylation up-regulates → | HABP4 PThr375 | phosphorylation down-regulates ⊣ | HABP4 | 14699138 | SIGNOR-249254 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCD | phosphorylation → down-regulates activity | HABP4 | SIGNOR-249248 |
| PRKCQ | phosphorylation → down-regulates activity | HABP4 | SIGNOR-249256 |
| PRKCZ | phosphorylation → down-regulates activity | HABP4 | SIGNOR-249251 |
| PRKCA | phosphorylation → down-regulates activity | HABP4 | SIGNOR-249252 |
| PRKCB | phosphorylation → down-regulates activity | HABP4 | SIGNOR-249253 |
| PRKCQ | phosphorylation → down-regulates activity | HABP4 | SIGNOR-249250 |
| PRKCG | phosphorylation → down-regulates activity | HABP4 | SIGNOR-249255 |
| PRKCA | phosphorylation → down-regulates activity | HABP4 | SIGNOR-249246 |
| PRKCB | phosphorylation → down-regulates activity | HABP4 | SIGNOR-249247 |
| PRKCZ | phosphorylation → down-regulates activity | HABP4 | SIGNOR-249257 |
| PRKCG | phosphorylation → down-regulates activity | HABP4 | SIGNOR-249249 |
| PRKCD | phosphorylation → down-regulates activity | HABP4 | SIGNOR-249254 |
