Entity Details

Name PPM1L
ID Q5SGD2
Role phosphatase
Enzymatic Domains
PPM-type phosphatase 92-351
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PPM1LMAP3K7–dephosphorylation
down-regulates activity		12556533SIGNOR-277114
PPM1LERN1–dephosphorylation
up-regulates activity		24327956SIGNOR-277074
PPM1LMAP3K5Thr838GINPCTEtFTGTLQYdephosphorylation
down-regulates		17456047SIGNOR-154554
PPM1LCERT1–dephosphorylation
up-regulates activity		18165232SIGNOR-277113
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PPM1Ldephosphorylation
down-regulates
⊣
MAP3K5
PThr838		dephosphorylation
up-regulates
→		MAP3K517456047SIGNOR-154554
Regulator Mechanism/Effect Target SIGNOR-ID
PPM1Ldephosphorylation
→
down-regulates activity 		MAP3K7SIGNOR-277114
PPM1Ldephosphorylation
→
up-regulates activity 		ERN1SIGNOR-277074
PPM1Ldephosphorylation
img/direct_inhibition.png
down-regulates 		MAP3K5SIGNOR-154554
PPM1Ldephosphorylation
→
up-regulates activity 		CERT1SIGNOR-277113