Entity Details

Name MAP3K21
ID Q5TCX8
Role kinase
Enzymatic Domains
SH3 38-102
PROSITE-ProRule
Protein kinase 124-401
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAP3K21CHUK–phosphorylation
down-regulates activity		26859459SIGNOR-279067
MAP3K21MAP2K1Ser218VSGQLIDsMANSFVGphosphorylation
up-regulates activity		23319808SIGNOR-260767
MAP3K21MAP2K1Ser222LIDSMANsFVGTRSYphosphorylation
up-regulates activity		23319808SIGNOR-260768
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAP3K21phosphorylation
up-regulates
→
MAP2K1
PSer218		phosphorylation
up-regulates
→		MAP2K123319808SIGNOR-260767
MAP3K21phosphorylation
up-regulates
→
MAP2K1
PSer222		phosphorylation
up-regulates
→		MAP2K123319808SIGNOR-260768
Regulator Mechanism/Effect Target SIGNOR-ID
MAP3K21phosphorylation
→
down-regulates activity 		CHUKSIGNOR-279067
MAP3K21phosphorylation
→
up-regulates activity 		MAP2K1SIGNOR-260767
MAP3K21phosphorylation
→
up-regulates activity 		MAP2K1SIGNOR-260768