| Name | CDC42BPA |
| ID | Q5VT25 |
| Role | kinase |
| Enzymatic Domains |
AGC-kinase C-terminal 344-414 PROSITE-ProRule
PH 1082-1201 PROSITE-ProRule
CNH 1227-1499 PROSITE-ProRule
CRIB 1571-1584 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDC42BPA | MYL2 | Ser19 | GANSNVFsMFEQTQI | phosphorylation up-regulates activity | 9418861 | SIGNOR-250723 |
| CDC42BPA | MYL9 | Ser20 | KRPQRATsNVFAMFD | phosphorylation up-regulates | 19851336 | SIGNOR-188781 |
| CDC42BPA | MYL9 | Thr19 | KKRPQRAtSNVFAMF | phosphorylation up-regulates | 19851336 | SIGNOR-188785 |
| CDC42BPA | LIMK1 | Thr508 | PDRKKRYtVVGNPYW | phosphorylation up-regulates activity | 11340065 | SIGNOR-250721 |
| CDC42BPA | LIMK2 | Thr505 | NDRKKRYtVVGNPYW | phosphorylation up-regulates activity | 11340065 | SIGNOR-107584 |
| CDC42BPA | CDC42BPA | Ser234 | MEDGTVQsSVAVGTP | phosphorylation up-regulates activity | 11283256 | SIGNOR-275974 |
| CDC42BPA | CDC42BPA | Thr240 | QSSVAVGtPDYISPE | phosphorylation up-regulates activity | 11283256 | SIGNOR-275975 |
| CDC42BPA | CDC42BPA | Thr403 | HLPFVGFtYTSSCVL | phosphorylation up-regulates activity | 11283256 | SIGNOR-275973 |
| CDC42BPA | PPP1R12C | Thr560 | MRQSRRStQGVTLTD | phosphorylation down-regulates activity | 11399775 | SIGNOR-250724 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDC42BPA | phosphorylation up-regulates → | MYL2 PSer19 | phosphorylation up-regulates → | MYL2 | 9418861 | SIGNOR-250723 |
| CDC42BPA | phosphorylation up-regulates → | MYL9 PSer20 | phosphorylation up-regulates → | MYL9 | 19851336 | SIGNOR-188781 |
| CDC42BPA | phosphorylation up-regulates → | MYL9 PThr19 | phosphorylation up-regulates → | MYL9 | 19851336 | SIGNOR-188785 |
| CDC42BPA | phosphorylation up-regulates → | LIMK1 PThr508 | phosphorylation up-regulates → | LIMK1 | 11340065 | SIGNOR-250721 |
| CDC42BPA | phosphorylation up-regulates → | LIMK2 PThr505 | phosphorylation up-regulates → | LIMK2 | 11340065 | SIGNOR-107584 |
| CDC42BPA | phosphorylation up-regulates → | CDC42BPA PSer234 | phosphorylation up-regulates → | CDC42BPA | 11283256 | SIGNOR-275974 |
| CDC42BPA | phosphorylation up-regulates → | CDC42BPA PThr240 | phosphorylation up-regulates → | CDC42BPA | 11283256 | SIGNOR-275975 |
| CDC42BPA | phosphorylation up-regulates → | CDC42BPA PThr403 | phosphorylation up-regulates → | CDC42BPA | 11283256 | SIGNOR-275973 |
| CDC42BPA | phosphorylation up-regulates → | PPP1R12C PThr560 | phosphorylation down-regulates ⊣ | PPP1R12C | 11399775 | SIGNOR-250724 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDC42BPA | phosphorylation → up-regulates activity | MYL2 | SIGNOR-250723 |
| CDC42BPA | phosphorylation → up-regulates | MYL9 | SIGNOR-188781 |
| CDC42BPA | phosphorylation → up-regulates | MYL9 | SIGNOR-188785 |
| CDC42BPA | phosphorylation → up-regulates activity | LIMK1 | SIGNOR-250721 |
| CDC42BPA | phosphorylation → up-regulates activity | LIMK2 | SIGNOR-107584 |
| CDC42BPA | phosphorylation → up-regulates activity | CDC42BPA | SIGNOR-275974 |
| CDC42BPA | phosphorylation → up-regulates activity | CDC42BPA | SIGNOR-275975 |
| CDC42BPA | phosphorylation → up-regulates activity | CDC42BPA | SIGNOR-275973 |
| CDC42BPA | phosphorylation → down-regulates activity | PPP1R12C | SIGNOR-250724 |