Entity Details

Name DAB2IP
ID Q5VWQ8
Role substrate
Enzymatic Domains
PH 101-202
PROSITE-ProRule
C2 193-311
PROSITE-ProRule
Ras-GAP 387-595
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
RIPK1DAB2IPSer728
View in OncoXplorer
PSPARSSsYSEANEPphosphorylation
up-regulates activity		17389591SIGNOR-259976
RIPK1DAB2IPSer728
View in OncoXplorer
PSPARSSsYSEANEPphosphorylation
up-regulates activity		27858941SIGNOR-254763
AKT1DAB2IPSer971STRLRQQsSSSKGDSphosphorylation
down-regulates activity		27858941SIGNOR-254780
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
RIPK1phosphorylation
up-regulates
→
DAB2IP
PSer728		phosphorylation
up-regulates
→		DAB2IP17389591SIGNOR-259976
RIPK1phosphorylation
up-regulates
→
DAB2IP
PSer728		phosphorylation
up-regulates
→		DAB2IP27858941SIGNOR-254763
AKT1phosphorylation
up-regulates
→
DAB2IP
PSer971		phosphorylation
down-regulates
⊣		DAB2IP27858941SIGNOR-254780
Regulator Mechanism/Effect Target SIGNOR-ID
RIPK1phosphorylation
→
up-regulates activity 		DAB2IPSIGNOR-259976
RIPK1phosphorylation
→
up-regulates activity 		DAB2IPSIGNOR-254763
AKT1phosphorylation
→
down-regulates activity 		DAB2IPSIGNOR-254780