Entity Details

Name CDCA2
ID Q69YH5
Role substrate
Enzymatic Domains
PP1-binding 389-449
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AURKBCDCA2Ser981RRKSFCIsTLANTKAphosphorylation
down-regulates activity		32938714SIGNOR-274001
AURKBCDCA2Ser893SETKVRRsTRLQKDLphosphorylation
down-regulates activity		23746640SIGNOR-280191
AURKBCDCA2Ser542KKINRRKsQETKCTKphosphorylation
down-regulates activity		32938714SIGNOR-274002
AURKBCDCA2Ser977
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EPGKRRKsFCISTLAphosphorylation
down-regulates activity		32938714SIGNOR-274004
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AURKBphosphorylation
up-regulates
→
CDCA2
PSer981		phosphorylation
down-regulates
⊣		CDCA232938714SIGNOR-274001
AURKBphosphorylation
up-regulates
→
CDCA2
PSer893		phosphorylation
down-regulates
⊣		CDCA223746640SIGNOR-280191
AURKBphosphorylation
up-regulates
→
CDCA2
PSer542		phosphorylation
down-regulates
⊣		CDCA232938714SIGNOR-274002
AURKBphosphorylation
up-regulates
→
CDCA2
PSer977		phosphorylation
down-regulates
⊣		CDCA232938714SIGNOR-274004
Regulator Mechanism/Effect Target SIGNOR-ID
AURKBphosphorylation
→
down-regulates activity 		CDCA2SIGNOR-274001
AURKBphosphorylation
→
down-regulates activity 		CDCA2SIGNOR-280191
AURKBphosphorylation
→
down-regulates activity 		CDCA2SIGNOR-274002
AURKBphosphorylation
→
down-regulates activity 		CDCA2SIGNOR-274004