| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK8 | RCSD1 | Ser68 | GQNGEEKsPPNASHP | phosphorylation down-regulates activity | 15850461 | SIGNOR-263085 |
| MAPK13 | RCSD1 | Ser68 | GQNGEEKsPPNASHP | phosphorylation down-regulates activity | 15850461 | SIGNOR-263084 |
| MAPK8 | RCSD1 | Ser83 | PKFKVKSsPLIEKLQ | phosphorylation down-regulates activity | 15850461 | SIGNOR-263086 |
| MAPKAPK2 | RCSD1 | Ser244 | PPLRRSPsRTEKQEE | phosphorylation down-regulates activity | 15850461 | SIGNOR-263080 |
| MAPKAPK3 | RCSD1 | Ser179 | RRFRRSQsDCGELGD | phosphorylation down-regulates activity | 15850461 | SIGNOR-263081 |
| MAPKAPK2 | RCSD1 | Ser179 | RRFRRSQsDCGELGD | phosphorylation down-regulates activity | 15850461 | SIGNOR-263079 |
| MAPK12 | RCSD1 | Ser108 | LPGASPKsPGLKAMV | phosphorylation down-regulates activity | 15850461 | SIGNOR-263083 |
| MAPKAPK3 | RCSD1 | Ser244 | PPLRRSPsRTEKQEE | phosphorylation down-regulates activity | 15850461 | SIGNOR-263082 |
| MAPK8 | RCSD1 | Ser216 | SKSKAPGsPLSSEGA | phosphorylation down-regulates activity | 15850461 | SIGNOR-263087 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK8 | phosphorylation up-regulates → | RCSD1 PSer68 | phosphorylation down-regulates ⊣ | RCSD1 | 15850461 | SIGNOR-263085 |
| MAPK13 | phosphorylation up-regulates → | RCSD1 PSer68 | phosphorylation down-regulates ⊣ | RCSD1 | 15850461 | SIGNOR-263084 |
| MAPK8 | phosphorylation up-regulates → | RCSD1 PSer83 | phosphorylation down-regulates ⊣ | RCSD1 | 15850461 | SIGNOR-263086 |
| MAPKAPK2 | phosphorylation up-regulates → | RCSD1 PSer244 | phosphorylation down-regulates ⊣ | RCSD1 | 15850461 | SIGNOR-263080 |
| MAPKAPK3 | phosphorylation up-regulates → | RCSD1 PSer179 | phosphorylation down-regulates ⊣ | RCSD1 | 15850461 | SIGNOR-263081 |
| MAPKAPK2 | phosphorylation up-regulates → | RCSD1 PSer179 | phosphorylation down-regulates ⊣ | RCSD1 | 15850461 | SIGNOR-263079 |
| MAPK12 | phosphorylation up-regulates → | RCSD1 PSer108 | phosphorylation down-regulates ⊣ | RCSD1 | 15850461 | SIGNOR-263083 |
| MAPKAPK3 | phosphorylation up-regulates → | RCSD1 PSer244 | phosphorylation down-regulates ⊣ | RCSD1 | 15850461 | SIGNOR-263082 |
| MAPK8 | phosphorylation up-regulates → | RCSD1 PSer216 | phosphorylation down-regulates ⊣ | RCSD1 | 15850461 | SIGNOR-263087 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK8 | phosphorylation → down-regulates activity | RCSD1 | SIGNOR-263085 |
| MAPK13 | phosphorylation → down-regulates activity | RCSD1 | SIGNOR-263084 |
| MAPK8 | phosphorylation → down-regulates activity | RCSD1 | SIGNOR-263086 |
| MAPKAPK2 | phosphorylation → down-regulates activity | RCSD1 | SIGNOR-263080 |
| MAPKAPK3 | phosphorylation → down-regulates activity | RCSD1 | SIGNOR-263081 |
| MAPKAPK2 | phosphorylation → down-regulates activity | RCSD1 | SIGNOR-263079 |
| MAPK12 | phosphorylation → down-regulates activity | RCSD1 | SIGNOR-263083 |
| MAPKAPK3 | phosphorylation → down-regulates activity | RCSD1 | SIGNOR-263082 |
| MAPK8 | phosphorylation → down-regulates activity | RCSD1 | SIGNOR-263087 |
