| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PINK1 | ZNF746 | Ser613 | APPDPFKsPASKGPL | phosphorylation up-regulates activity | 32169097 | SIGNOR-278267 |
| PINK1 | ZNF746 | Ser613 | APPDPFKsPASKGPL | phosphorylation down-regulates quantity by destabilization | 28122242 | SIGNOR-273725 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PINK1 | phosphorylation up-regulates → | ZNF746 PSer613 | phosphorylation up-regulates → | ZNF746 | 32169097 | SIGNOR-278267 |
| PINK1 | phosphorylation up-regulates → | ZNF746 PSer613 | phosphorylation down-regulates ⊣ | ZNF746 | 28122242 | SIGNOR-273725 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PINK1 | phosphorylation → up-regulates activity | ZNF746 | SIGNOR-278267 |
| PINK1 | phosphorylation![]() down-regulates quantity by destabilization | ZNF746 | SIGNOR-273725 |