Entity Details

Name PKN3
ID Q6P5Z2
Role kinase
Enzymatic Domains
REM-1 1 5-80
PROSITE-ProRule
REM-1 2 93-163
PROSITE-ProRule
REM-1 3 165-245
PROSITE-ProRule
Protein kinase 559-818
PROSITE-ProRule
AGC-kinase C-terminal 819-889
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PKN3BCAR1Ser428PAEGKRLsASSTGSTphosphorylation
unknown		30422386SIGNOR-264574
PKN3ARHGAP18Ser156QKRVETVsQTLRKKNphosphorylation
up-regulates activity		33092266SIGNOR-264571
PKN3ARHGAP18Thr154AVQKRVEtVSQTLRKphosphorylation
up-regulates activity		33092266SIGNOR-264570
PKN3ARHGAP18Thr158RVETVSQtLRKKNKQphosphorylation
up-regulates activity		33092266SIGNOR-264572
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PKN3phosphorylation
up-regulates
→
BCAR1
PSer428		phosphorylation
down-regulates
⊣		BCAR130422386SIGNOR-264574
PKN3phosphorylation
up-regulates
→
ARHGAP18
PSer156		phosphorylation
up-regulates
→		ARHGAP1833092266SIGNOR-264571
PKN3phosphorylation
up-regulates
→
ARHGAP18
PThr154		phosphorylation
up-regulates
→		ARHGAP1833092266SIGNOR-264570
PKN3phosphorylation
up-regulates
→
ARHGAP18
PThr158		phosphorylation
up-regulates
→		ARHGAP1833092266SIGNOR-264572
Regulator Mechanism/Effect Target SIGNOR-ID
PKN3phosphorylation
→
unknown 		BCAR1SIGNOR-264574
PKN3phosphorylation
→
up-regulates activity 		ARHGAP18SIGNOR-264571
PKN3phosphorylation
→
up-regulates activity 		ARHGAP18SIGNOR-264570
PKN3phosphorylation
→
up-regulates activity 		ARHGAP18SIGNOR-264572