| Name | ULK3 |
| ID | Q6PHR2 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 14-270 PROSITE-ProRule
MIT 1 280-348
MIT 2 375-444 |
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|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ULK3 | GLI1 | – | phosphorylation up-regulates activity | 19878745 | SIGNOR-260797 | |
| ULK3 | GLI2 | – | phosphorylation up-regulates activity | 19878745 | SIGNOR-260798 | |
| ULK3 | GLI3 | – | phosphorylation up-regulates activity | 19878745 | SIGNOR-260799 | |
| ULK3 | IST1 | – | phosphorylation down-regulates activity | 26011858 | SIGNOR-278205 | |
| ULK3 | ULK3 | Ser300 | KKDQEGDsAAALSLY | phosphorylation up-regulates activity | 20643644 | SIGNOR-260793 |
| ULK3 | ULK3 | Ser350 | ELKAIVSsSNQALLR | phosphorylation up-regulates activity | 20643644 | SIGNOR-260794 |
| ULK3 | ULK3 | Ser384 | RLLAALEvASAAMAK | phosphorylation up-regulates activity | 20643644 | SIGNOR-260795 |
| ULK3 | ULK3 | Ser464 | DKEGLSEsVRSSCTL | phosphorylation up-regulates activity | 20643644 | SIGNOR-260796 |
| ULK3 | CHMP4C | – | phosphorylation down-regulates activity | 26011858 | SIGNOR-279771 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ULK3 | phosphorylation up-regulates → | ULK3 PSer300 | phosphorylation up-regulates → | ULK3 | 20643644 | SIGNOR-260793 |
| ULK3 | phosphorylation up-regulates → | ULK3 PSer350 | phosphorylation up-regulates → | ULK3 | 20643644 | SIGNOR-260794 |
| ULK3 | phosphorylation up-regulates → | ULK3 PSer384 | phosphorylation up-regulates → | ULK3 | 20643644 | SIGNOR-260795 |
| ULK3 | phosphorylation up-regulates → | ULK3 PSer464 | phosphorylation up-regulates → | ULK3 | 20643644 | SIGNOR-260796 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ULK3 | phosphorylation → up-regulates activity | GLI1 | SIGNOR-260797 |
| ULK3 | phosphorylation → up-regulates activity | GLI2 | SIGNOR-260798 |
| ULK3 | phosphorylation → up-regulates activity | GLI3 | SIGNOR-260799 |
| ULK3 | phosphorylation → down-regulates activity | IST1 | SIGNOR-278205 |
| ULK3 | phosphorylation → up-regulates activity | ULK3 | SIGNOR-260793 |
| ULK3 | phosphorylation → up-regulates activity | ULK3 | SIGNOR-260794 |
| ULK3 | phosphorylation → up-regulates activity | ULK3 | SIGNOR-260795 |
| ULK3 | phosphorylation → up-regulates activity | ULK3 | SIGNOR-260796 |
| ULK3 | phosphorylation → down-regulates activity | CHMP4C | SIGNOR-279771 |