| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | TENT2 | Ser116 | LSGERRYsMPPLFHT | phosphorylation down-regulates activity | 31057087 | SIGNOR-259405 |
| PRKACG | TENT2 | Ser116 | LSGERRYsMPPLFHT | phosphorylation down-regulates activity | 31057087 | SIGNOR-259404 |
| PRKACB | TENT2 | Ser116 | LSGERRYsMPPLFHT | phosphorylation down-regulates activity | 31057087 | SIGNOR-259403 |
| PRKACA | TENT2 | Ser116 | LSGERRYsMPPLFHT | phosphorylation down-regulates activity | 31057087 | SIGNOR-259402 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | phosphorylation up-regulates → | TENT2 PSer116 | phosphorylation down-regulates ⊣ | TENT2 | 31057087 | SIGNOR-259405 |
| PRKACG | phosphorylation up-regulates → | TENT2 PSer116 | phosphorylation down-regulates ⊣ | TENT2 | 31057087 | SIGNOR-259404 |
| PRKACB | phosphorylation up-regulates → | TENT2 PSer116 | phosphorylation down-regulates ⊣ | TENT2 | 31057087 | SIGNOR-259403 |
| PRKACA | phosphorylation up-regulates → | TENT2 PSer116 | phosphorylation down-regulates ⊣ | TENT2 | 31057087 | SIGNOR-259402 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT1 | phosphorylation → down-regulates activity | TENT2 | SIGNOR-259405 |
| PRKACG | phosphorylation → down-regulates activity | TENT2 | SIGNOR-259404 |
| PRKACB | phosphorylation → down-regulates activity | TENT2 | SIGNOR-259403 |
| PRKACA | phosphorylation → down-regulates activity | TENT2 | SIGNOR-259402 |