| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6KB1 | RICTOR | Thr1135 | NRRIRTLtEPSVDFN | phosphorylation down-regulates | 19995915 | SIGNOR-161995 |
| GSK3A | RICTOR | Thr1695 | EAEAVLAtPPKQPIV | phosphorylation down-regulates quantity by destabilization | 25897075 | SIGNOR-276899 |
| GSK3B | RICTOR | Thr1695 | EAEAVLAtPPKQPIV | phosphorylation down-regulates quantity by destabilization | 25897075 | SIGNOR-276898 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6KB1 | phosphorylation up-regulates → | RICTOR PThr1135 | phosphorylation down-regulates ⊣ | RICTOR | 19995915 | SIGNOR-161995 |
| GSK3A | phosphorylation up-regulates → | RICTOR PThr1695 | phosphorylation down-regulates ⊣ | RICTOR | 25897075 | SIGNOR-276899 |
| GSK3B | phosphorylation up-regulates → | RICTOR PThr1695 | phosphorylation down-regulates ⊣ | RICTOR | 25897075 | SIGNOR-276898 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| RPS6KB1 | phosphorylation![]() down-regulates | RICTOR | SIGNOR-161995 |
| GSK3A | phosphorylation![]() down-regulates quantity by destabilization | RICTOR | SIGNOR-276899 |
| GSK3B | phosphorylation![]() down-regulates quantity by destabilization | RICTOR | SIGNOR-276898 |