Entity Details

Name CRTC1
ID Q6UUV9
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAP3K1CRTC1–phosphorylation
up-regulates		18784253SIGNOR-180816
AMPKCRTC1–phosphorylation
down-regulates		21331044SIGNOR-216529
PRKAA1CRTC1–phosphorylation
down-regulates		21331044SIGNOR-172136
SIK1CRTC1Ser167MTPTQPEsFSSGSQDphosphorylation
down-regulates		16817901SIGNOR-147669
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SIK1phosphorylation
up-regulates
→
CRTC1
PSer167		phosphorylation
down-regulates
⊣		CRTC116817901SIGNOR-147669
Regulator Mechanism/Effect Target SIGNOR-ID
MAP3K1phosphorylation
→
up-regulates 		CRTC1SIGNOR-180816
AMPKphosphorylation
img/direct_inhibition.png
down-regulates 		CRTC1SIGNOR-216529
PRKAA1phosphorylation
img/direct_inhibition.png
down-regulates 		CRTC1SIGNOR-172136
SIK1phosphorylation
img/direct_inhibition.png
down-regulates 		CRTC1SIGNOR-147669