| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| STK3 | MOB1B | Thr12 | FGSRSSKtFKPKKNI | phosphorylation up-regulates | 21808241 | SIGNOR-175813 |
| STK3 | MOB1B | Thr35 | LLKHAEAtLGSGNLR | phosphorylation up-regulates | 21808241 | SIGNOR-175817 |
| STK4 | MOB1B | Thr35 | LLKHAEAtLGSGNLR | phosphorylation up-regulates | 23431053 | SIGNOR-201318 |
| STK4 | MOB1B | Thr35 | LLKHAEAtLGSGNLR | phosphorylation up-regulates | 21808241 | SIGNOR-175841 |
| STK3/4 | MOB1B | – | phosphorylation up-regulates | 21808241 | SIGNOR-270221 | |
| PTPN5 | MOB1B | Tyr26 | IPEGSHQyELLKHAE | dephosphorylation up-regulates activity | 28675297 | SIGNOR-277058 |
| STK3 | MOB1B | Thr12 | FGSRSSKtFKPKKNI | phosphorylation up-regulates | 23431053 | SIGNOR-201290 |
| STK3 | MOB1B | Thr35 | LLKHAEAtLGSGNLR | phosphorylation up-regulates | 23431053 | SIGNOR-201294 |
| STK4 | MOB1B | Thr12 | FGSRSSKtFKPKKNI | phosphorylation up-regulates | 23431053 | SIGNOR-201314 |
| STK4 | MOB1B | Thr12 | FGSRSSKtFKPKKNI | phosphorylation up-regulates | 21808241 | SIGNOR-175837 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| STK3 | phosphorylation up-regulates → | MOB1B PThr12 | phosphorylation up-regulates → | MOB1B | 21808241 | SIGNOR-175813 |
| STK3 | phosphorylation up-regulates → | MOB1B PThr35 | phosphorylation up-regulates → | MOB1B | 21808241 | SIGNOR-175817 |
| STK4 | phosphorylation up-regulates → | MOB1B PThr35 | phosphorylation up-regulates → | MOB1B | 23431053 | SIGNOR-201318 |
| STK4 | phosphorylation up-regulates → | MOB1B PThr35 | phosphorylation up-regulates → | MOB1B | 21808241 | SIGNOR-175841 |
| PTPN5 | dephosphorylation down-regulates ⊣ | MOB1B PTyr26 | dephosphorylation down-regulates ⊣ | MOB1B | 28675297 | SIGNOR-277058 |
| STK3 | phosphorylation up-regulates → | MOB1B PThr12 | phosphorylation up-regulates → | MOB1B | 23431053 | SIGNOR-201290 |
| STK3 | phosphorylation up-regulates → | MOB1B PThr35 | phosphorylation up-regulates → | MOB1B | 23431053 | SIGNOR-201294 |
| STK4 | phosphorylation up-regulates → | MOB1B PThr12 | phosphorylation up-regulates → | MOB1B | 23431053 | SIGNOR-201314 |
| STK4 | phosphorylation up-regulates → | MOB1B PThr12 | phosphorylation up-regulates → | MOB1B | 21808241 | SIGNOR-175837 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| STK3 | phosphorylation → up-regulates | MOB1B | SIGNOR-175813 |
| STK3 | phosphorylation → up-regulates | MOB1B | SIGNOR-175817 |
| STK4 | phosphorylation → up-regulates | MOB1B | SIGNOR-201318 |
| STK4 | phosphorylation → up-regulates | MOB1B | SIGNOR-175841 |
| STK3/4 | phosphorylation → up-regulates | MOB1B | SIGNOR-270221 |
| PTPN5 | dephosphorylation → up-regulates activity | MOB1B | SIGNOR-277058 |
| STK3 | phosphorylation → up-regulates | MOB1B | SIGNOR-201290 |
| STK3 | phosphorylation → up-regulates | MOB1B | SIGNOR-201294 |
| STK4 | phosphorylation → up-regulates | MOB1B | SIGNOR-201314 |
| STK4 | phosphorylation → up-regulates | MOB1B | SIGNOR-175837 |
