| Name | RASGRP2 |
| ID | Q7LDG7 |
| Role | substrate |
| Enzymatic Domains |
N-terminal Ras-GEF 4-126 PROSITE-ProRule
Ras-GEF 154-387 PROSITE-ProRule
EF-hand 1 426-461 PROSITE-ProRule
EF-hand 2 455-490 PROSITE-ProRule |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | RASGRP2 | Ser394 | RSKSSPTsPTSCTPP | phosphorylation down-regulates activity | 27107697 | SIGNOR-279537 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | phosphorylation up-regulates → | RASGRP2 PSer394 | phosphorylation down-regulates ⊣ | RASGRP2 | 27107697 | SIGNOR-279537 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK1 | phosphorylation → down-regulates activity | RASGRP2 | SIGNOR-279537 |