| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT | SH3RF1 | Ser304 | KNTKKRHsFTSLTMA | phosphorylation down-regulates | 17535800 | SIGNOR-155229 |
| AKT1 | SH3RF1 | Ser304 | KNTKKRHsFTSLTMA | phosphorylation down-regulates | 17535800 | SIGNOR-252501 |
| AKT2 | SH3RF1 | Ser304 | KNTKKRHsFTSLTMA | phosphorylation down-regulates | 17535800 | SIGNOR-155233 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT | phosphorylation up-regulates → | SH3RF1 PSer304 | phosphorylation down-regulates ⊣ | SH3RF1 | 17535800 | SIGNOR-155229 |
| AKT1 | phosphorylation up-regulates → | SH3RF1 PSer304 | phosphorylation down-regulates ⊣ | SH3RF1 | 17535800 | SIGNOR-252501 |
| AKT2 | phosphorylation up-regulates → | SH3RF1 PSer304 | phosphorylation down-regulates ⊣ | SH3RF1 | 17535800 | SIGNOR-155233 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT | phosphorylation down-regulates | SH3RF1 | SIGNOR-155229 |
| AKT1 | phosphorylation down-regulates | SH3RF1 | SIGNOR-252501 |
| AKT2 | phosphorylation down-regulates | SH3RF1 | SIGNOR-155233 |
