Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CDK2	ZC3HC1	Ser395 View in OncoXplorer	PGLEVPSsPLRKAKR	phosphorylation down-regulates	17389604	SIGNOR-154051
CDK1	ZC3HC1	Ser395 View in OncoXplorer	PGLEVPSsPLRKAKR	phosphorylation down-regulates	17389604	SIGNOR-154047
CyclinB/CDK1	ZC3HC1	Ser395 View in OncoXplorer	PGLEVPSsPLRKAKR	phosphorylation down-regulates	17389604	SIGNOR-216880

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CDK2	phosphorylation up-regulates →	ZC3HC1 PSer395	phosphorylation down-regulates ⊣	ZC3HC1	17389604	SIGNOR-154051
CDK1	phosphorylation up-regulates →	ZC3HC1 PSer395	phosphorylation down-regulates ⊣	ZC3HC1	17389604	SIGNOR-154047
CyclinB/CDK1	phosphorylation up-regulates →	ZC3HC1 PSer395	phosphorylation down-regulates ⊣	ZC3HC1	17389604	SIGNOR-216880

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CDK2	phosphorylation down-regulates	ZC3HC1	SIGNOR-154051
CDK1	phosphorylation down-regulates	ZC3HC1	SIGNOR-154047
CyclinB/CDK1	phosphorylation down-regulates	ZC3HC1	SIGNOR-216880