| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | ZC3HC1 | Ser395 | PGLEVPSsPLRKAKR | phosphorylation down-regulates | 17389604 | SIGNOR-216880 |
| CDK2 | ZC3HC1 | Ser395 | PGLEVPSsPLRKAKR | phosphorylation down-regulates | 17389604 | SIGNOR-154051 |
| CDK1 | ZC3HC1 | Ser395 | PGLEVPSsPLRKAKR | phosphorylation down-regulates | 17389604 | SIGNOR-154047 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | phosphorylation up-regulates → | ZC3HC1 PSer395 | phosphorylation down-regulates ⊣ | ZC3HC1 | 17389604 | SIGNOR-216880 |
| CDK2 | phosphorylation up-regulates → | ZC3HC1 PSer395 | phosphorylation down-regulates ⊣ | ZC3HC1 | 17389604 | SIGNOR-154051 |
| CDK1 | phosphorylation up-regulates → | ZC3HC1 PSer395 | phosphorylation down-regulates ⊣ | ZC3HC1 | 17389604 | SIGNOR-154047 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CyclinB/CDK1 | phosphorylation down-regulates | ZC3HC1 | SIGNOR-216880 |
| CDK2 | phosphorylation down-regulates | ZC3HC1 | SIGNOR-154051 |
| CDK1 | phosphorylation down-regulates | ZC3HC1 | SIGNOR-154047 |
