| Name | HIPK1 |
| ID | Q86Z02 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 190-518 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| HIPK1 | PAGE4 | Thr51 | PGQEREGtPPIEERK | phosphorylation up-regulates activity | 24559171 | SIGNOR-260929 |
| HIPK1 | MYB | – | phosphorylation down-regulates activity | 19646965 | SIGNOR-279189 | |
| HIPK1 | DAXX | Ser668 | KKICTLPsPPSPLAS | phosphorylation down-regulates activity | 12529400 | SIGNOR-260842 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| HIPK1 | phosphorylation up-regulates → | PAGE4 PThr51 | phosphorylation up-regulates → | PAGE4 | 24559171 | SIGNOR-260929 |
| HIPK1 | phosphorylation up-regulates → | DAXX PSer668 | phosphorylation down-regulates ⊣ | DAXX | 12529400 | SIGNOR-260842 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| HIPK1 | phosphorylation → up-regulates activity | PAGE4 | SIGNOR-260929 |
| HIPK1 | phosphorylation → down-regulates activity | MYB | SIGNOR-279189 |
| HIPK1 | phosphorylation → down-regulates activity | DAXX | SIGNOR-260842 |