Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
MAP4K3	TFEB	Ser3	sRIGLRMQ	phosphorylation down-regulates activity	29507340	SIGNOR-278282
MAP4K3	IQGAP1	Ser480	NTVWKQLsSSVTGLT	phosphorylation up-regulates activity	31431460	SIGNOR-277479
MAP4K3	PRKCQ	Thr538	LGDAKTNtFCGTPDY	phosphorylation up-regulates	21983831	SIGNOR-176744
MAP4K3	MAP3K1	–		phosphorylation up-regulates	9820741	SIGNOR-61814
MAP4K3	MAP4K3	Ser170	ATIAKRKsFIGTPYW	phosphorylation up-regulates	20227368	SIGNOR-164103

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
MAP4K3	phosphorylation up-regulates →	TFEB PSer3	phosphorylation down-regulates ⊣	TFEB	29507340	SIGNOR-278282
MAP4K3	phosphorylation up-regulates →	IQGAP1 PSer480	phosphorylation up-regulates →	IQGAP1	31431460	SIGNOR-277479
MAP4K3	phosphorylation up-regulates →	PRKCQ PThr538	phosphorylation up-regulates →	PRKCQ	21983831	SIGNOR-176744
MAP4K3	phosphorylation up-regulates →	MAP4K3 PSer170	phosphorylation up-regulates →	MAP4K3	20227368	SIGNOR-164103

Regulator	Mechanism/Effect	Target	SIGNOR-ID
MAP4K3	phosphorylation → down-regulates activity	TFEB	SIGNOR-278282
MAP4K3	phosphorylation → up-regulates activity	IQGAP1	SIGNOR-277479
MAP4K3	phosphorylation → up-regulates	PRKCQ	SIGNOR-176744
MAP4K3	phosphorylation → up-regulates	MAP3K1	SIGNOR-61814
MAP4K3	phosphorylation → up-regulates	MAP4K3	SIGNOR-164103