Entity Details

Name CCDC50
ID Q8IVM0
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
EGFRCCDC50Tyr217MAEEKKAyKKAKEREphosphorylation
down-regulates activity		19059208SIGNOR-262850
LCKCCDC50Tyr279TDGEDADyTHFTNQQphosphorylation
down-regulates activity		19059208SIGNOR-262854
LCKCCDC50Tyr304SSHKGFHyKHphosphorylation
down-regulates activity		19059208SIGNOR-262855
EGFRCCDC50Tyr304SSHKGFHyKHphosphorylation
down-regulates activity		19059208SIGNOR-262852
EGFRCCDC50Tyr279TDGEDADyTHFTNQQphosphorylation
down-regulates activity		19059208SIGNOR-262851
LCKCCDC50Tyr217MAEEKKAyKKAKEREphosphorylation
down-regulates activity		19059208SIGNOR-262853
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
EGFRphosphorylation
up-regulates
→
CCDC50
PTyr217		phosphorylation
down-regulates
⊣		CCDC5019059208SIGNOR-262850
LCKphosphorylation
up-regulates
→
CCDC50
PTyr279		phosphorylation
down-regulates
⊣		CCDC5019059208SIGNOR-262854
LCKphosphorylation
up-regulates
→
CCDC50
PTyr304		phosphorylation
down-regulates
⊣		CCDC5019059208SIGNOR-262855
EGFRphosphorylation
up-regulates
→
CCDC50
PTyr304		phosphorylation
down-regulates
⊣		CCDC5019059208SIGNOR-262852
EGFRphosphorylation
up-regulates
→
CCDC50
PTyr279		phosphorylation
down-regulates
⊣		CCDC5019059208SIGNOR-262851
LCKphosphorylation
up-regulates
→
CCDC50
PTyr217		phosphorylation
down-regulates
⊣		CCDC5019059208SIGNOR-262853
Regulator Mechanism/Effect Target SIGNOR-ID
EGFRphosphorylation
→
down-regulates activity 		CCDC50SIGNOR-262850
LCKphosphorylation
→
down-regulates activity 		CCDC50SIGNOR-262854
LCKphosphorylation
→
down-regulates activity 		CCDC50SIGNOR-262855
EGFRphosphorylation
→
down-regulates activity 		CCDC50SIGNOR-262852
EGFRphosphorylation
→
down-regulates activity 		CCDC50SIGNOR-262851
LCKphosphorylation
→
down-regulates activity 		CCDC50SIGNOR-262853