Entity Details

Name EGFR_Tyr217
ID Q8IVM0
Role residue
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
LCKCCDC50Tyr217MAEEKKAyKKAKEREphosphorylation
down-regulates activity		19059208SIGNOR-262853
EGFRCCDC50Tyr217MAEEKKAyKKAKEREphosphorylation
down-regulates activity		19059208SIGNOR-262850
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
LCKphosphorylation
up-regulates
→
CCDC50
PTyr217		phosphorylation
down-regulates
⊣		CCDC5019059208SIGNOR-262853
EGFRphosphorylation
up-regulates
→
CCDC50
PTyr217		phosphorylation
down-regulates
⊣		CCDC5019059208SIGNOR-262850
Regulator Mechanism/Effect Target SIGNOR-ID
LCKphosphorylation
→
down-regulates activity 		CCDC50SIGNOR-262853
EGFRphosphorylation
→
down-regulates activity 		CCDC50SIGNOR-262850