Entity Details

Name EGFR_Tyr279
ID Q8IVM0
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
LCKCCDC50Tyr279TDGEDADyTHFTNQQphosphorylation
down-regulates activity		19059208SIGNOR-262854
EGFRCCDC50Tyr279TDGEDADyTHFTNQQphosphorylation
down-regulates activity		19059208SIGNOR-262851
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
LCKphosphorylation
up-regulates
→
CCDC50
PTyr279		phosphorylation
down-regulates
⊣		CCDC5019059208SIGNOR-262854
EGFRphosphorylation
up-regulates
→
CCDC50
PTyr279		phosphorylation
down-regulates
⊣		CCDC5019059208SIGNOR-262851
Regulator Mechanism/Effect Target SIGNOR-ID
LCKphosphorylation
→
down-regulates activity 		CCDC50SIGNOR-262854
EGFRphosphorylation
→
down-regulates activity 		CCDC50SIGNOR-262851