Entity Details

Name LCK_Tyr217
ID Q8IVM0
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
EGFRCCDC50Tyr217MAEEKKAyKKAKEREphosphorylation
down-regulates activity		19059208SIGNOR-262850
LCKCCDC50Tyr217MAEEKKAyKKAKEREphosphorylation
down-regulates activity		19059208SIGNOR-262853
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
EGFRphosphorylation
up-regulates
→
CCDC50
PTyr217		phosphorylation
down-regulates
⊣		CCDC5019059208SIGNOR-262850
LCKphosphorylation
up-regulates
→
CCDC50
PTyr217		phosphorylation
down-regulates
⊣		CCDC5019059208SIGNOR-262853
Regulator Mechanism/Effect Target SIGNOR-ID
EGFRphosphorylation
→
down-regulates activity 		CCDC50SIGNOR-262850
LCKphosphorylation
→
down-regulates activity 		CCDC50SIGNOR-262853