Entity Details

Name FUNDC1
ID Q8IVP5
Role substrate
Enzymatic Domains
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
ULK1FUNDC1Ser17
View in OncoXplorer
DYESDDDsYEVLDLTphosphorylation
up-regulates activity		27757847SIGNOR-279001
CSNK2A1FUNDC1Ser13
View in OncoXplorer
PPPQDYEsDDDSYEVphosphorylation
down-regulates activity		24746696SIGNOR-273622
ULK1FUNDC1Ser17
View in OncoXplorer
DYESDDDsYEVLDLTphosphorylation
up-regulates activity		24671035SIGNOR-273606
PGAM5FUNDC1–dephosphorylation
up-regulates activity		24746696SIGNOR-273654
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
ULK1phosphorylation
up-regulates
→
FUNDC1
PSer17		phosphorylation
up-regulates
→		FUNDC127757847SIGNOR-279001
CSNK2A1phosphorylation
up-regulates
→
FUNDC1
PSer13		phosphorylation
down-regulates
⊣		FUNDC124746696SIGNOR-273622
ULK1phosphorylation
up-regulates
→
FUNDC1
PSer17		phosphorylation
up-regulates
→		FUNDC124671035SIGNOR-273606
Regulator Mechanism/Effect Target SIGNOR-ID
ULK1phosphorylation
→
up-regulates activity 		FUNDC1SIGNOR-279001
CSNK2A1phosphorylation
→
down-regulates activity 		FUNDC1SIGNOR-273622
ULK1phosphorylation
→
up-regulates activity 		FUNDC1SIGNOR-273606
PGAM5dephosphorylation
→
up-regulates activity 		FUNDC1SIGNOR-273654