Entity Details

Name TEX14
ID Q8IWB6
Role substrate
Enzymatic Domains
Protein kinase 227-518
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PLK1TEX14Ser437QKAATVKsDIYSFSMphosphorylation
down-regulates quantity by destabilization		22405274SIGNOR-273529
PLK1TEX14–phosphorylation
down-regulates quantity by destabilization		22405274SIGNOR-279646
CDK1TEX14–phosphorylation
up-regulates activity		22405274SIGNOR-279677
CDK1TEX14Thr618EEASSPStGQPSLCSphosphorylation
down-regulates quantity by destabilization		22405274SIGNOR-273523
CDK1TEX14Thr728NLNNMSTtEEYLISKphosphorylation
down-regulates quantity by destabilization		22405274SIGNOR-273522
CDK1TEX14Thr727SNLNNMStTEEYLISphosphorylation
down-regulates quantity by destabilization		22405274SIGNOR-273524
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PLK1phosphorylation
up-regulates
→
TEX14
PSer437		phosphorylation
down-regulates
⊣		TEX1422405274SIGNOR-273529
CDK1phosphorylation
up-regulates
→
TEX14
PThr618		phosphorylation
down-regulates
⊣		TEX1422405274SIGNOR-273523
CDK1phosphorylation
up-regulates
→
TEX14
PThr728		phosphorylation
down-regulates
⊣		TEX1422405274SIGNOR-273522
CDK1phosphorylation
up-regulates
→
TEX14
PThr727		phosphorylation
down-regulates
⊣		TEX1422405274SIGNOR-273524
Regulator Mechanism/Effect Target SIGNOR-ID
PLK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		TEX14SIGNOR-273529
PLK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		TEX14SIGNOR-279646
CDK1phosphorylation
→
up-regulates activity 		TEX14SIGNOR-279677
CDK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		TEX14SIGNOR-273523
CDK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		TEX14SIGNOR-273522
CDK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		TEX14SIGNOR-273524