| Name | BRSK2 |
| ID | Q8IWQ3 |
| Role | substrate |
| Enzymatic Domains |
Protein kinase 19-270 PROSITE-ProRule
UBA 297-339 |
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|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| STK11 | BRSK2 | Thr174 | VGDSLLEtSCGSPHY | phosphorylation up-regulates | 14976552 | SIGNOR-122485 |
| PKA | BRSK2 | Thr260 | VDAARRLtLEHIQKH | phosphorylation up-regulates activity | 16870137 | SIGNOR-276056 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| STK11 | phosphorylation up-regulates → | BRSK2 PThr174 | phosphorylation up-regulates → | BRSK2 | 14976552 | SIGNOR-122485 |
| PKA | phosphorylation up-regulates → | BRSK2 PThr260 | phosphorylation up-regulates → | BRSK2 | 16870137 | SIGNOR-276056 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| STK11 | phosphorylation → up-regulates | BRSK2 | SIGNOR-122485 |
| PKA | phosphorylation → up-regulates activity | BRSK2 | SIGNOR-276056 |