Entity Details

Name LMTK2
ID Q8IWU2
Role kinase
Enzymatic Domains
Protein kinase 137-407
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
LMTK2CFTRSer737EPLERRLsLVPDSEQphosphorylation
down-regulates activity		24727471SIGNOR-278227
LMTK2PPP1CAThr320NPGGRPItPPRNSAKphosphorylation
down-regulates activity		12393858SIGNOR-94631
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
LMTK2phosphorylation
up-regulates
→
CFTR
PSer737		phosphorylation
down-regulates
⊣		CFTR24727471SIGNOR-278227
LMTK2phosphorylation
up-regulates
→
PPP1CA
PThr320		phosphorylation
down-regulates
⊣		PPP1CA12393858SIGNOR-94631
Regulator Mechanism/Effect Target SIGNOR-ID
LMTK2phosphorylation
→
down-regulates activity 		CFTRSIGNOR-278227
LMTK2phosphorylation
→
down-regulates activity 		PPP1CASIGNOR-94631