| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | SIRT2 | Tyr104 | RSPSTGLyDNLEKYH | phosphorylation down-regulates quantity by destabilization | 24996174 | SIGNOR-263104 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | phosphorylation up-regulates → | SIRT2 PTyr104 | phosphorylation down-regulates ⊣ | SIRT2 | 24996174 | SIGNOR-263104 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SRC | phosphorylation![]() down-regulates quantity by destabilization | SIRT2 | SIGNOR-263104 |