| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ABL1 | ABI1 | Tyr213 | PPTVPNDyMTSPARL | phosphorylation up-regulates | 21320496 | SIGNOR-172017 |
| PTEN | ABI1 | Tyr213 | PPTVPNDyMTSPARL | dephosphorylation down-regulates quantity by destabilization | 32673396 | SIGNOR-276948 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ABL1 | phosphorylation up-regulates → | ABI1 PTyr213 | phosphorylation up-regulates → | ABI1 | 21320496 | SIGNOR-172017 |
| PTEN | dephosphorylation down-regulates ⊣ | ABI1 PTyr213 | dephosphorylation up-regulates → | ABI1 | 32673396 | SIGNOR-276948 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ABL1 | phosphorylation → up-regulates | ABI1 | SIGNOR-172017 |
| PTEN | dephosphorylation![]() down-regulates quantity by destabilization | ABI1 | SIGNOR-276948 |