Entity Details

Name CyclinB/CDK1_Ser216
ID Q8IZP0
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CyclinB/CDK1ABI1Ser216VPNDYMTsPARLGSQphosphorylation
down-regulates activity		21900237SIGNOR-264452
PTENABI1Ser216VPNDYMTsPARLGSQdephosphorylation
down-regulates quantity by destabilization		32673396SIGNOR-276949
CDK1ABI1Ser216VPNDYMTsPARLGSQphosphorylation
down-regulates activity		21900237SIGNOR-264421
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CyclinB/CDK1phosphorylation
up-regulates
→
ABI1
PSer216		phosphorylation
down-regulates
⊣		ABI121900237SIGNOR-264452
PTENdephosphorylation
down-regulates
⊣
ABI1
PSer216		dephosphorylation
up-regulates
→		ABI132673396SIGNOR-276949
CDK1phosphorylation
up-regulates
→
ABI1
PSer216		phosphorylation
down-regulates
⊣		ABI121900237SIGNOR-264421
Regulator Mechanism/Effect Target SIGNOR-ID
CyclinB/CDK1phosphorylation
→
down-regulates activity 		ABI1SIGNOR-264452
PTENdephosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		ABI1SIGNOR-276949
CDK1phosphorylation
→
down-regulates activity 		ABI1SIGNOR-264421