Entity Details

Name STAG2
ID Q8N3U4
Role substrate
Enzymatic Domains
SCD 293-378
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SSU72STAG2Ser1224PASIMDEsVLGVSMFdephosphorylation
up-regulates activity		20818333SIGNOR-275531
PLK1STAG2Ser1137KRLRPEDsFMSVYPMdephosphorylation
down-regulates activity		15737063SIGNOR-275534
PLK1STAG2Ser1224PASIMDEsVLGVSMFdephosphorylation
down-regulates activity		15737063SIGNOR-275532
PLK1STAG2Thr1109MWLSREQtLHTPVMMdephosphorylation
down-regulates activity		15737063SIGNOR-275533
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SSU72dephosphorylation
down-regulates
⊣
STAG2
PSer1224		dephosphorylation
down-regulates
⊣		STAG220818333SIGNOR-275531
PLK1dephosphorylation
down-regulates
⊣
STAG2
PSer1137		dephosphorylation
up-regulates
→		STAG215737063SIGNOR-275534
PLK1dephosphorylation
down-regulates
⊣
STAG2
PSer1224		dephosphorylation
up-regulates
→		STAG215737063SIGNOR-275532
PLK1dephosphorylation
down-regulates
⊣
STAG2
PThr1109		dephosphorylation
up-regulates
→		STAG215737063SIGNOR-275533
Regulator Mechanism/Effect Target SIGNOR-ID
SSU72dephosphorylation
→
up-regulates activity 		STAG2SIGNOR-275531
PLK1dephosphorylation
→
down-regulates activity 		STAG2SIGNOR-275534
PLK1dephosphorylation
→
down-regulates activity 		STAG2SIGNOR-275532
PLK1dephosphorylation
→
down-regulates activity 		STAG2SIGNOR-275533