| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK1 | STAG2 | Ser1224 | PASIMDEsVLGVSMF | dephosphorylation down-regulates activity | 15737063 | SIGNOR-275532 |
| SSU72 | STAG2 | Ser1224 | PASIMDEsVLGVSMF | dephosphorylation up-regulates activity | 20818333 | SIGNOR-275531 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK1 | dephosphorylation down-regulates ⊣ | STAG2 PSer1224 | dephosphorylation up-regulates → | STAG2 | 15737063 | SIGNOR-275532 |
| SSU72 | dephosphorylation down-regulates ⊣ | STAG2 PSer1224 | dephosphorylation down-regulates ⊣ | STAG2 | 20818333 | SIGNOR-275531 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PLK1 | dephosphorylation → down-regulates activity | STAG2 | SIGNOR-275532 |
| SSU72 | dephosphorylation → up-regulates activity | STAG2 | SIGNOR-275531 |