| Name | CAMKK1 |
| ID | Q8N5S9 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 128-409 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CAMKK1 | AKT1 | Thr308 | KDGATMKtFCGTPEY | phosphorylation up-regulates activity | 10833263 | SIGNOR-252609 |
| CAMKK1 | PRKAA1 | Thr183 | SDGEFLRtSCGSPNY | phosphorylation up-regulates | 21918180 | SIGNOR-176598 |
| CAMKK1 | CAMK1 | Thr177 | DPGSVLStACGTPGY | phosphorylation up-regulates activity | 8253780 | SIGNOR-250717 |
| CAMKK1 | CAMK4 | – | phosphorylation up-regulates | 10770941 | SIGNOR-232181 | |
| CAMKK1 | CAMK4 | Thr200 | EHQVLMKtVCGTPGY | phosphorylation up-regulates | 15143065 | SIGNOR-124732 |
| CAMKK1 | CAMK4 | Thr200 | EHQVLMKtVCGTPGY | phosphorylation up-regulates | 15769749 | SIGNOR-134649 |
| CAMKK1 | CAMK1D | Thr180 | GKGDVMStACGTPGY | phosphorylation up-regulates activity | 12935886 | SIGNOR-250715 |
| CAMKK1 | BRSK1 | – | phosphorylation up-regulates activity | 18324781 | SIGNOR-280202 | |
| CAMKK1 | AKT | Thr308 | KDGATMKtFCGTPEY | phosphorylation up-regulates activity | 10833263 | SIGNOR-250714 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CAMKK1 | phosphorylation up-regulates → | AKT1 PThr308 | phosphorylation up-regulates → | AKT1 | 10833263 | SIGNOR-252609 |
| CAMKK1 | phosphorylation up-regulates → | PRKAA1 PThr183 | phosphorylation up-regulates → | PRKAA1 | 21918180 | SIGNOR-176598 |
| CAMKK1 | phosphorylation up-regulates → | CAMK1 PThr177 | phosphorylation up-regulates → | CAMK1 | 8253780 | SIGNOR-250717 |
| CAMKK1 | phosphorylation up-regulates → | CAMK4 PThr200 | phosphorylation up-regulates → | CAMK4 | 15143065 | SIGNOR-124732 |
| CAMKK1 | phosphorylation up-regulates → | CAMK4 PThr200 | phosphorylation up-regulates → | CAMK4 | 15769749 | SIGNOR-134649 |
| CAMKK1 | phosphorylation up-regulates → | CAMK1D PThr180 | phosphorylation up-regulates → | CAMK1D | 12935886 | SIGNOR-250715 |
| CAMKK1 | phosphorylation up-regulates → | AKT PThr308 | phosphorylation up-regulates → | AKT | 10833263 | SIGNOR-250714 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CAMKK1 | phosphorylation → up-regulates activity | AKT1 | SIGNOR-252609 |
| CAMKK1 | phosphorylation → up-regulates | PRKAA1 | SIGNOR-176598 |
| CAMKK1 | phosphorylation → up-regulates activity | CAMK1 | SIGNOR-250717 |
| CAMKK1 | phosphorylation → up-regulates | CAMK4 | SIGNOR-232181 |
| CAMKK1 | phosphorylation → up-regulates | CAMK4 | SIGNOR-124732 |
| CAMKK1 | phosphorylation → up-regulates | CAMK4 | SIGNOR-134649 |
| CAMKK1 | phosphorylation → up-regulates activity | CAMK1D | SIGNOR-250715 |
| CAMKK1 | phosphorylation → up-regulates activity | BRSK1 | SIGNOR-280202 |
| CAMKK1 | phosphorylation → up-regulates activity | AKT | SIGNOR-250714 |