Entity Details

Name SIRT6
ID Q8N6T7
Role substrate
Enzymatic Domains
Deacetylase sirtuin-type 27-272
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKT1SIRT6Ser338
View in OncoXplorer
PKRERPTsPAPHRPPphosphorylation
down-regulates activity		25074979SIGNOR-278465
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKT1phosphorylation
up-regulates
→
SIRT6
PSer338		phosphorylation
down-regulates
⊣		SIRT625074979SIGNOR-278465
Regulator Mechanism/Effect Target SIGNOR-ID
AKT1phosphorylation
→
down-regulates activity 		SIRT6SIGNOR-278465