| Name | CSNK1A1L |
| ID | Q8N752 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 17-285 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK1A1L | LRP6 | – | phosphorylation up-regulates | 19293931 | SIGNOR-184699 | |
| CSNK1A1L | LRP6 | – | phosphorylation up-regulates | 21606194 | SIGNOR-173853 | |
| CSNK1A1L | NFAT5 | Ser158 | LLDNSRMsCQDEGCG | phosphorylation up-regulates activity | 18411282 | SIGNOR-274111 |
| CSNK1A1L | GLI2 | – | phosphorylation up-regulates | 16481469 | SIGNOR-144551 | |
| CSNK1A1L | GLI2 | – | phosphorylation up-regulates | 18698484 | SIGNOR-179972 | |
| CSNK1A1L | GLI3 | – | phosphorylation up-regulates | 16481469 | SIGNOR-144554 | |
| CSNK1A1L | CTNNB1 | Ser45 | GATTTAPsLSGKGNP | phosphorylation down-regulates | 12000790 | SIGNOR-87430 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK1A1L | phosphorylation up-regulates → | NFAT5 PSer158 | phosphorylation up-regulates → | NFAT5 | 18411282 | SIGNOR-274111 |
| CSNK1A1L | phosphorylation up-regulates → | CTNNB1 PSer45 | phosphorylation down-regulates ⊣ | CTNNB1 | 12000790 | SIGNOR-87430 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK1A1L | phosphorylation → up-regulates | LRP6 | SIGNOR-184699 |
| CSNK1A1L | phosphorylation → up-regulates | LRP6 | SIGNOR-173853 |
| CSNK1A1L | phosphorylation → up-regulates activity | NFAT5 | SIGNOR-274111 |
| CSNK1A1L | phosphorylation → up-regulates | GLI2 | SIGNOR-144551 |
| CSNK1A1L | phosphorylation → up-regulates | GLI2 | SIGNOR-179972 |
| CSNK1A1L | phosphorylation → up-regulates | GLI3 | SIGNOR-144554 |
| CSNK1A1L | phosphorylation down-regulates | CTNNB1 | SIGNOR-87430 |