| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP6C | CGAS | Ser435 | KHLDKFSsYHVKTAF | dephosphorylation down-regulates activity | 32474700 | SIGNOR-276990 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP6C | dephosphorylation down-regulates ⊣ | CGAS PSer435 | dephosphorylation up-regulates → | CGAS | 32474700 | SIGNOR-276990 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP6C | dephosphorylation → down-regulates activity | CGAS | SIGNOR-276990 |