Entity Details

Name SYK_Tyr215
ID Q8N884
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
BLKCGASTyr215LLNTGSYyEHVKISAphosphorylation
down-regulates activity		30356214SIGNOR-275844
SYKCGASTyr215LLNTGSYyEHVKISAphosphorylation
up-regulates activity		36252040SIGNOR-277845
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
BLKphosphorylation
up-regulates
→
CGAS
PTyr215		phosphorylation
down-regulates
⊣		CGAS30356214SIGNOR-275844
SYKphosphorylation
up-regulates
→
CGAS
PTyr215		phosphorylation
up-regulates
→		CGAS36252040SIGNOR-277845
Regulator Mechanism/Effect Target SIGNOR-ID
BLKphosphorylation
→
down-regulates activity 		CGASSIGNOR-275844
SYKphosphorylation
→
up-regulates activity 		CGASSIGNOR-277845