Entity Details

Name MLKL_Thr357
ID Q8NB16
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
RIPK3MLKLThr357FELRKTQtSMSLGTTphosphorylation
up-regulates activity		24012422SIGNOR-266429
RIPK3MLKLThr357FELRKTQtSMSLGTTphosphorylation
up-regulates activity		24012422SIGNOR-266438
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
RIPK3phosphorylation
up-regulates
→
MLKL
PThr357		phosphorylation
up-regulates
→		MLKL24012422SIGNOR-266429
RIPK3phosphorylation
up-regulates
→
MLKL
PThr357		phosphorylation
up-regulates
→		MLKL24012422SIGNOR-266438
Regulator Mechanism/Effect Target SIGNOR-ID
RIPK3phosphorylation
→
up-regulates activity 		MLKLSIGNOR-266429
RIPK3phosphorylation
→
up-regulates activity 		MLKLSIGNOR-266438