Entity Details

Name MLKL_Tyr376
ID Q8NB16
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AXLMLKLTyr376DRVKSTAyLSPQELEphosphorylation
up-regulates quantity by stabilization		31230815SIGNOR-274119
MERTKMLKLTyr376DRVKSTAyLSPQELEphosphorylation
up-regulates quantity by stabilization		31230815SIGNOR-274118
TYRO3MLKLTyr376DRVKSTAyLSPQELEphosphorylation
up-regulates quantity by stabilization		31230815SIGNOR-274120
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AXLphosphorylation
up-regulates
→
MLKL
PTyr376		phosphorylation
up-regulates
→		MLKL31230815SIGNOR-274119
MERTKphosphorylation
up-regulates
→
MLKL
PTyr376		phosphorylation
up-regulates
→		MLKL31230815SIGNOR-274118
TYRO3phosphorylation
up-regulates
→
MLKL
PTyr376		phosphorylation
up-regulates
→		MLKL31230815SIGNOR-274120
Regulator Mechanism/Effect Target SIGNOR-ID
AXLphosphorylation
→
up-regulates quantity by stabilization 		MLKLSIGNOR-274119
MERTKphosphorylation
→
up-regulates quantity by stabilization 		MLKLSIGNOR-274118
TYRO3phosphorylation
→
up-regulates quantity by stabilization 		MLKLSIGNOR-274120