Entity Details

Name PCSK9
ID Q8NBP7
Role substrate
Enzymatic Domains
Inhibitor I9 77-149

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Peptidase S8 155-461
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
FAM20CPCSK9Ser47ELVLALRsEEDGLAEphosphorylation
up-regulates activity
31553664SIGNOR-278935
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
FAM20Cphosphorylation
up-regulates
→
PCSK9
PSer47
phosphorylation
up-regulates
→
PCSK931553664SIGNOR-278935
Regulator Mechanism/Effect Target SIGNOR-ID
FAM20Cphosphorylation
→
up-regulates activity
PCSK9SIGNOR-278935