| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK5 | PIK3C3 | Thr159 | DGSEPTKtPGRTSST | phosphorylation down-regulates | 20513426 | SIGNOR-165772 |
| CDK1 | PIK3C3 | Thr159 | DGSEPTKtPGRTSST | phosphorylation down-regulates | 20513426 | SIGNOR-165768 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK5 | phosphorylation up-regulates → | PIK3C3 PThr159 | phosphorylation down-regulates ⊣ | PIK3C3 | 20513426 | SIGNOR-165772 |
| CDK1 | phosphorylation up-regulates → | PIK3C3 PThr159 | phosphorylation down-regulates ⊣ | PIK3C3 | 20513426 | SIGNOR-165768 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK5 | phosphorylation![]() down-regulates | PIK3C3 | SIGNOR-165772 |
| CDK1 | phosphorylation![]() down-regulates | PIK3C3 | SIGNOR-165768 |