| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AURKB | KNL1 | Ser60 | KKNSRRVsFADTIKV | phosphorylation down-regulates | 20471944 | SIGNOR-165506 |
| AURKB | KNL1 | Ser24 | RPVRRRHsSILKPPR | phosphorylation down-regulates | 20471944 | SIGNOR-165502 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AURKB | phosphorylation up-regulates → | KNL1 PSer60 | phosphorylation down-regulates ⊣ | KNL1 | 20471944 | SIGNOR-165506 |
| AURKB | phosphorylation up-regulates → | KNL1 PSer24 | phosphorylation down-regulates ⊣ | KNL1 | 20471944 | SIGNOR-165502 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AURKB | phosphorylation down-regulates | KNL1 | SIGNOR-165506 |
| AURKB | phosphorylation down-regulates | KNL1 | SIGNOR-165502 |
