| Name | NEK11 |
| ID | Q8NG66 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 29-287 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| NEK11 | CDC25A | Ser82 | GSSESTDsGFCLDSP | phosphorylation down-regulates | 19734889 | SIGNOR-187867 |
| NEK11 | CDC25A | Ser88 | DSGFCLDsPGPLDSK | phosphorylation down-regulates | 19734889 | SIGNOR-187871 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| NEK11 | phosphorylation up-regulates → | CDC25A PSer82 | phosphorylation down-regulates ⊣ | CDC25A | 19734889 | SIGNOR-187867 |
| NEK11 | phosphorylation up-regulates → | CDC25A PSer88 | phosphorylation down-regulates ⊣ | CDC25A | 19734889 | SIGNOR-187871 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| NEK11 | phosphorylation down-regulates | CDC25A | SIGNOR-187867 |
| NEK11 | phosphorylation down-regulates | CDC25A | SIGNOR-187871 |