Entity Details

Name GSK3A_Thr53
ID Q8NHW3
Role residue
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
GSK3BMAFAThr53PPGSLSStPLSTPCSphosphorylation
down-regulates quantity by destabilization		18042454SIGNOR-159466
GSK3BMAFAThr53PPGSLSStPLSTPCSphosphorylation
up-regulates activity		18042454SIGNOR-159450
GSK3AMAFAThr53PPGSLSStPLSTPCSphosphorylation
up-regulates activity		18042454SIGNOR-159373
GSK3AMAFAThr53PPGSLSStPLSTPCSphosphorylation
down-regulates quantity by destabilization		18042454SIGNOR-159394
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GSK3Bphosphorylation
up-regulates
→
MAFA
PThr53		phosphorylation
down-regulates
⊣		MAFA18042454SIGNOR-159466
GSK3Bphosphorylation
up-regulates
→
MAFA
PThr53		phosphorylation
up-regulates
→		MAFA18042454SIGNOR-159450
GSK3Aphosphorylation
up-regulates
→
MAFA
PThr53		phosphorylation
up-regulates
→		MAFA18042454SIGNOR-159373
GSK3Aphosphorylation
up-regulates
→
MAFA
PThr53		phosphorylation
down-regulates
⊣		MAFA18042454SIGNOR-159394
Regulator Mechanism/Effect Target SIGNOR-ID
GSK3Bphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		MAFASIGNOR-159466
GSK3Bphosphorylation
→
up-regulates activity 		MAFASIGNOR-159450
GSK3Aphosphorylation
→
up-regulates activity 		MAFASIGNOR-159373
GSK3Aphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		MAFASIGNOR-159394