Entity Details

Name GSK3A_Thr57
ID Q8NHW3
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
GSK3BMAFAThr57LSSTPLStPCSSVPSphosphorylation
down-regulates quantity by destabilization		18042454SIGNOR-159470
GSK3AMAFAThr57LSSTPLStPCSSVPSphosphorylation
up-regulates activity		18042454SIGNOR-159377
GSK3BMAFAThr57LSSTPLStPCSSVPSphosphorylation
up-regulates activity		18042454SIGNOR-159454
GSK3AMAFAThr57LSSTPLStPCSSVPSphosphorylation
down-regulates quantity by destabilization		18042454SIGNOR-159398
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GSK3Bphosphorylation
up-regulates
→
MAFA
PThr57		phosphorylation
down-regulates
⊣		MAFA18042454SIGNOR-159470
GSK3Aphosphorylation
up-regulates
→
MAFA
PThr57		phosphorylation
up-regulates
→		MAFA18042454SIGNOR-159377
GSK3Bphosphorylation
up-regulates
→
MAFA
PThr57		phosphorylation
up-regulates
→		MAFA18042454SIGNOR-159454
GSK3Aphosphorylation
up-regulates
→
MAFA
PThr57		phosphorylation
down-regulates
⊣		MAFA18042454SIGNOR-159398
Regulator Mechanism/Effect Target SIGNOR-ID
GSK3Bphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		MAFASIGNOR-159470
GSK3Aphosphorylation
→
up-regulates activity 		MAFASIGNOR-159377
GSK3Bphosphorylation
→
up-regulates activity 		MAFASIGNOR-159454
GSK3Aphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		MAFASIGNOR-159398