Entity Details

Name GSK3B_Ser49
ID Q8NHW3
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
GSK3AMAFASer49CHRLPPGsLSSTPLSphosphorylation
down-regulates quantity by destabilization		18042454SIGNOR-159381
GSK3BMAFASer49CHRLPPGsLSSTPLSphosphorylation
up-regulates activity		18042454SIGNOR-159442
GSK3AMAFASer49CHRLPPGsLSSTPLSphosphorylation
up-regulates activity		18042454SIGNOR-159365
GSK3BMAFASer49CHRLPPGsLSSTPLSphosphorylation
down-regulates quantity by destabilization		18042454SIGNOR-159458
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GSK3Aphosphorylation
up-regulates
→
MAFA
PSer49		phosphorylation
down-regulates
⊣		MAFA18042454SIGNOR-159381
GSK3Bphosphorylation
up-regulates
→
MAFA
PSer49		phosphorylation
up-regulates
→		MAFA18042454SIGNOR-159442
GSK3Aphosphorylation
up-regulates
→
MAFA
PSer49		phosphorylation
up-regulates
→		MAFA18042454SIGNOR-159365
GSK3Bphosphorylation
up-regulates
→
MAFA
PSer49		phosphorylation
down-regulates
⊣		MAFA18042454SIGNOR-159458
Regulator Mechanism/Effect Target SIGNOR-ID
GSK3Aphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		MAFASIGNOR-159381
GSK3Bphosphorylation
→
up-regulates activity 		MAFASIGNOR-159442
GSK3Aphosphorylation
→
up-regulates activity 		MAFASIGNOR-159365
GSK3Bphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		MAFASIGNOR-159458