Entity Details

Name GSK3B_Ser61
ID Q8NHW3
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
GSK3AMAFASer61PLSTPCSsVPSSPSFphosphorylation
up-regulates activity		18042454SIGNOR-159369
GSK3AMAFASer61PLSTPCSsVPSSPSFphosphorylation
down-regulates quantity by destabilization		18042454SIGNOR-159390
GSK3BMAFASer61PLSTPCSsVPSSPSFphosphorylation
up-regulates activity		18042454SIGNOR-159446
GSK3BMAFASer61PLSTPCSsVPSSPSFphosphorylation
down-regulates quantity by destabilization		18042454SIGNOR-159462
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GSK3Aphosphorylation
up-regulates
→
MAFA
PSer61		phosphorylation
up-regulates
→		MAFA18042454SIGNOR-159369
GSK3Aphosphorylation
up-regulates
→
MAFA
PSer61		phosphorylation
down-regulates
⊣		MAFA18042454SIGNOR-159390
GSK3Bphosphorylation
up-regulates
→
MAFA
PSer61		phosphorylation
up-regulates
→		MAFA18042454SIGNOR-159446
GSK3Bphosphorylation
up-regulates
→
MAFA
PSer61		phosphorylation
down-regulates
⊣		MAFA18042454SIGNOR-159462
Regulator Mechanism/Effect Target SIGNOR-ID
GSK3Aphosphorylation
→
up-regulates activity 		MAFASIGNOR-159369
GSK3Aphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		MAFASIGNOR-159390
GSK3Bphosphorylation
→
up-regulates activity 		MAFASIGNOR-159446
GSK3Bphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		MAFASIGNOR-159462